Abstract: It is established a method for the simultaneous determination of 18 phthalate acid esters (PAEs) migration in paper cups of mouth-contact material by liquid liquid extraction-gas chromatography-mass spectrometry (LLE-GC-MS).PAEs in paper cups of mouth-contact material were extracted by saliva stimulant,and extract was extracted and enriched by liquid liquid extraction,with dichloromethane as the extracting solvent and benzyl benzoate as the internal standard,the solvent was evaporated in vacuum until it almost dry,constant volume was made with n-hexane.Then sample was injected by mode of pulse splitless,and tested by SIM mode of GC-MS.The correlation coefficients(R) of 18 PAEs were over 0.99,and the limits of detection were 2.7×10-8 g to 1.00×10-3 g.The recoveries of 18 PAEs were ranged from 73.4% to 114.4% and the relative standard deviations (RSDs) of results were in the range of 1.42%~8.72%.The method has advantage of recovery and repeatability,meet further the request for testing of PAEs in paper cups of mouth-contact material.