Abstract: The degradation property of cyanoethylated wastepaper(CSF) has been explored with microbiology experiment method.The results show that the cyanoethylated wastepaper can be effectively degraded by celluloses,and the degradation property is better than wastepaper.After 192 hours degradation by Trichoderma reesei cellulose,the weightlessness rate of CSF can reach 23.6%.The research on degradation features of reveals that cyanoethylated wastepaper can be effectively degraded by bacteria which are Bacillus subtilis (subsp) and Ochrobactrum sp.Under the optimum conditions 35 ℃,pH 11.0,25%—30% inoculum size and 50 g/L substrate concentration,degradation speed of cyanoethylated wastepaper can be firstly increased and then reduced; Degradation speed is lower after 12—14 days.After degradation by bacterium for 14 days,the content of reducing sugar remains about 0.030 mg/mL,and the weightlessness rate of cyanoethylated wastepaper is 29.57%