Abstract: This paper,based on conventional meteorological observation data in East China which from 123 conventional weather stations during 1964-2013 and digital elevation model (DEM),performed a detailed estimation in terrain,by using the method of 'golden mean comfort-index standard and analyzed the space-time distribution of regional climate comfort difference.The results provide a reference for the exploitation and utilization of regioal climate resources.It indicates that,the climate comfort-index are gradually reduced from low to high latitude and altitude,and from the coastal to the inland.Meanwhile,the most comfortable time of East China are the April and May in spring and the September and October in autumn.Besides,the biggest and the smallest annual changes of the climate comfort-index are the Shandong Province and the Fujian Province.In addition,there are 306100km2 area whith have the climate comfortable period as long as four months.