几种新型苯甲酰基脲类几丁质抑制剂的合成(Ⅰ)

Synthesis of some novel benzoylphenylurea chitin inhibitors (Ⅰ)

摘要: 以百菌清和卤代苯腈为原料经3～4步反应合成出2类共4个新型苯甲酰基脲类几丁质合成抑制剂6a-c和9a.两条路线的反应条件均温和,产率高.化合物的结构得到IR,MS,1HNMR,13CNMR,19FNMR,HRMS等波谱的证实.

Abstract: Four novel benzoylphenylurea chitin inhibitor derivatives 6a-c and 9,which belonging to two kind of compounds,have been synthesized from readily available starting material chlorothalonil 4 and halo benzenenitrile 1 via three to four steps.Two synthesis routes have some advantages such as mild temperature conditions,high yields.All the novel benzoylphenylureas compounds were confirmed by spectroscopic methods including IR,1H NMR,13C NMR and HRMS.