Abstract: The biological activity of methanol extractives of Sabina vulgris on Leucania separata Walker and Sitophilus zeamais Mots were tested in laboratory by feeding leaf disc with the extractives and deed-extractive mixture respectively.The extractives had evident antifeedant effect on L.separata.While,L.seoarata appeared visible toxicosis syndrome,12h after feeding the poisonous leaf discs,although the modified mortali-ties were no more than 30%.The used two concentraations of the extractives depressed the population of S.zeamais by over 80%.But the solvent acetone had some negative effect on the population reprodutive of S.zeamais adults.