Abstract: Gold catalysts dispersed on CexZr1-xO2 oxides were prepared by deposition precipitation method,and their structures were characterized by XRD.The catalytic activity of the catalyst for CO oxidation was evaluated.The effect of preparation conditions on catalytic activity was also studied,and the preparation conditions were optimized.The best result indicated that Au/CexZr1-xO2 prepared under the following conditions:Ce0.75Zr0.25O2 calcined at 550℃,and gold loading 4.7%,showed very high catalytic activity for CO oxidation at room temperature.The Au/CexZr1-xO2 catalyst was high resistance to moisture,1% CO in air could be oxidized to CO2 with 30%～40% conversions under high concentration CO conditions.