Abstract: By selecting the definition of dynamical and thermal tropopause as the boundaries between the stratosphere and troposphere,This article has used the Wei-formula in the isentropic coordinates,analyzed the fluxes of mass and ozone cross-tropopause in the East Asian region and found that the fluxes of mass and ozone in the East Asian region,overall the exchange of mass and ozone flux had obvious inter-decadal variation,the 44 years' change can be divided into three relatively stable time:years of 1958—1971,1972—1985 and 1986—2001.In the three time,the distribution of mass exchange anomaly performanced "-+-",the trend shows that the situation of mass flux exchange in the East Asian region first to enhancement after weakening.Near the Tarim Basin is the transmission gradually increased,and stratospheric and tropospheric mass exchange near the Northeast China Plains and the North China Plain of the East Asian region had also gone through a process of gradually increased,indicating that these regions in the mass exchange played an increasingly important role.