Abstract: Liquid phase oxidation of cyclohexane was carried out under mild reaction conditions catalyzied by MnxOy/SBA-3,using aqueous hydrogen peroxide as oxidant and acetic acid as solvent without adding any initiator.The effects of different solvents,reaction temperature and reaction time on cyclohexane oxidation were investigated.A reasonable substrate conversion (60.2%) and product (cyclohexanone/cyclohexanol) selectivity (72.2%/27.1%) were obtained under the optimum reaction conditions,which were 50mg catalyst,5mL H2O2 (30%),acetic acid as solvent,reaction temperature 373K;reaction time 10h.