Abstract: To prepare a solid dispersion for sustained release from extract of honeysuckle and study the characteristics of the release trial in vitro.Sustained release solid dispersions have been prepared by the solvent method,using bentonite as carriers.Ultraviolet spectrophotometry and release test were applied to determine the release degree of the extraction of honeysuckle with different release mediums.The solid dispersion prepared from extract of honeysuckle had a better effect of sustained drug release in artificial gastric juices and artificial intestinal juices,and its release profiles fitted the Weibull model.Using bentonite as carrier for the solid dispersions for extracts of honeysuckle has a better sustained release effect.