Abstract: Based on the ECMWF ERA-40 meridional wind and monthly mean ozone mass mixing ratio data over the global for 540 months from September 1957 to August 2002.By defining a series of Hadley circulation indexes for analysis the evolutionary rule and interactions between Hadley circulation and ozone.The results show that.① Among the defined Hadley circulation indexes,the correlation between NHCI and ozone is best,while HCI-ozone correlation takes second place.So we use power spectrum and coagulation spectrum to study the periodic correlation between NHCI-ozone.②The correlations between each Hadley circulation index and ozone concentration time series over Southern Hemisphere is best and over equator take second place and over Northern Hemisphere is less.③ The main correlation between NHCI and ozone concentration is obvious latitude zonal distribution.It indicates that the transport for ozone driving by MMC is inconsistent in different latitude.④ Both NHCI and ozone's seasonal change are very obvious and there are many resonance periods between them.Five to six months is the highlight resonance period and one year period is their respectively obvious period.The change of ozone concentration lags behind NHCI resonance and the lag time is latitude-variation.