Abstract: From December 2005 to November 2006,a total of 42 patients with POAG or ocular hypertension who took the treatment of tracoprost after they carried out the surgery or used other medicines.After 4-and 12-week treatment,the change of intraocular pressure was recorded using a Goldman electronic tonometer,and the safety indicators of travoprost,conjunctival congestion and eyelid skin pigmentation were recorded.Among the patients,59.6% (25) showed significant treatment effects,23.8% (10) had improvements and 16.6% (7) were not improved.The average basic intraocular pressure was 24.40 mm Hg,while after 4 weeks tracoprost treatment it reached 17.30mmHg,and after 12 weeks it was 15.90 mm Hg.Mild conjunctival congestions were found with 37 patients (76.25%),23.8% (10) have moderate conjunctival congestions.It shows that the treatment of tracoprost can achieve significant and stable effects on the patients with primary angle closure glaucoma and ocular hypertension.