丽江紫乌头中的二萜生物碱

Diterpenoid alkaloids from Aconitum episcopale Levl.

摘要: 对丽江紫乌头中的二萜生物碱进行研究.利用反复硅胶柱层析,重结晶等分离手段从中分离鉴定了6个二萜生物碱:查斯曼宁(chasmanineⅠ),塔拉萨敏(talatizamine Ⅱ),草乌甲素(crassicauline A Ⅲ),丽江乌头碱(foresaconitine Ⅳ),acoforestinine(Ⅴ),滇乌碱(yunaconitine Ⅵ).其中化合物Ⅰ、Ⅲ、Ⅳ、Ⅴ为首次从该种植物中分离得到.

Abstract: The diterpenoid alkaloids of Aconitum episcopale Levl.were studied and six diterpenoid alkaloids were isolated by silica column chromatography.The structures of theses compounds were elucidated as chasmanineⅠ,talatizamine Ⅱ,crassicauline A Ⅲ,foresaconitine Ⅳ,acoforestinine Ⅴ,yunaconitine Ⅵ by spectral methods.Compounds Ⅰ,Ⅲ,Ⅳ,Ⅴ were isolated from this plant for the first time.