姜酮的NMR解析

Chemical structure and its 1H NMR spectral analysis of zingiberone

摘要: 报道对生姜（Zingiber officinale）中分离得到的活性成分姜酮（1）,通过二维核磁共振谱（1H-1H COSY、HSQC、HMBC）完全解析1H NMR、13C NMR信号的结果.修订其13C NMR谱信号归属,并确证了姜酮（1）的化学结构.还讨论了不同溶剂（氘代甲醇、氘代氯仿、DMSO）对姜酮（1）侧链上相邻亚甲基质子,一个典型A2B2系统质子信号的影响,是溶剂对姜酮中质子偶合影响,对姜酮衍生物类的生物活性研究起重要作用.

Abstract: In this paper,the chemical structure of zingiberone (1),which a common compound isolated from Zingiber officinale was conformed and the 13C NMR signals of zingiberone (1) were assigned first time by 1D and 2D NMR techniques (1H-1H COSY,HSQC and HMBC).This paper described that 1H NMR signal figures of the protons of adjacent two methylene which should be a typical A2B2 system in zingiberone (1) were affected by different deuterated solvent,and probably reasons were also discussed.