Abstract: In order to improve teaching quality of medical cell biology after the credit system reform,we performed several innovations according to the course requirement after investigate the learning situation of students.First,we integratd related courses and selected teaching contents seriously.Second,we teached students with the teaching model selected by them.Third,we cultivated students’ self–study capability through the supplementary lecture,the study guide and the cyber source.The results showed that these methods could stimulate interest in learning,improved the self-learning ability and the quality of learning.