Abstract: Based on the British Hadley center SST,NASA ozone mass mixing ratio reanalysis during 1980—2015,calculating the IOB index and IOD index which characterize the dominating modes of tropical Indian Ocean SST interannual variability—Indian Ocean Basin (IOB) mode and Indian Ocean Dipole (IOD) mode,analyzing the correlation of tropical Indian Ocean SST anomalies and ozone mass mixing ratio in stratosphere over East Asia.And the impact of Tropical Indian Ocean temperature on the ozone layer in East Asia region also has been investigated in this paper.The result show:(1)the changes of tropical Indian Ocean SST have significant effects on stratospheric ozone distribution in East Asia,and it’s consistent whit the changing rules of IOB and IOD;(2)IOBI and IODI have a certain correlation with stratospheric ozone changes in East Asia,with a particularly significant correlation in the lower stratosphere (70 hPa) and middle stratosphere (40 hPa) especially during the spring and autumn seasons.