Abstract: In this paper, TiO₂-SiO₂ aerogel materials doped with metal ions W, Sn and V were prepared by sol-gel method. The samples were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), nitrogen adsorption-desorption curves and UV-Vis diffuse reflectance spectroscopy (UV-Vis DRS). It was found that the TiO₂-SiO₂ aerogels had more fluffy structure by doping metal ions. Photocatalytic degradation of acetamiprid by UV irradiation was carried out. The results showed that Sn doped TiO₂-SiO₂ aerogels exhibited the best photocatalytic degradation performance. The degradation rate of acetamiprid could reach 100% after 2 h of illumination. The formation of hydroxyl radical (•OH) on the surface of the catalyst during photocatalysis was confirmed by electron paramagnetic resonance spectroscopy (EPR). The experimental mechanism of decomposition products such as chloronicotinic acid and acetic acid can be obtained through hydroxylation, pyridine ring structure and bond breaking, and other processes such as oxidation and hydrolysis.