Abstract: The northeastern margin of the Tibetan Plateau (NETP) is the leading edge of the North-East expansion of the Tibetan Plateau. Studying the distribution characteristics of gravity anomalies in the NETP is of great significance for revealing the dynamic process of the Tibetan Plateau. Based on WGM2012 global gravity field model, in this paper the distribution characteristics of the different depths and different orders of Bouguer gravity anomaly are found by using the method of wavelet multi-scale analysis to analyze Bouguer gravity anomaly of the northeast edge of the Tibetan Plateau. The results show that with the increase of decomposition order numbers, the corresponding equivalent source depths increase, and the low frequency information is more outstanding. The Bouguer gravity anomaly in the study area has an obvious east-west partition phenomenon, showing a low phenomenon in the west and a high one in the east, which confirms the flow of crustal materials and the blocking effect of the rigid blocks around the Tibetan Plateau. The Qiangtang block shows a positive anomaly in the fourth-order detail field, which reflects the dynamic process of material melting and upwelling to the middle crust due to the temperature rise caused by the subduction and friction of the Indian plate. The distribution characteristics of gravity anomaly in each detail field of the Alxa block are similar to those of the Ordos block, indicating that the Alxa block was separated from the North China ancient land. Based on the distribution of the gravity anomaly, the depth-positions of the main fractures of the study area are analyzed, which found out that the western margin of Ordos, Gansu fault, and Longmenshan fault are surface faults; the Altun fault, the South Qilian suture, the Kunlun Mountains suture, and Haiyuan fault go through the upper-crust to the surface; the Badain jaran fracture mainly exists in the upper-crust, and the North Qilian suture extends from the middle crust to the surface.