Abstract: 30 mmol/L Na₂B₄O₇ and 10 mmol/L NaH₂PO₄ were the separating background solution (pH=8.64) consisting of 1.2% (V/V) triethanolamine, 0.3% (V/V) tetrahydrofuran, 2.0% (v/v) isopropanol as additives, with the high separation voltage (20 kV), detector wavelength (326 nm) and injection (3 s, 3447.38 Pa). Under this condition, a new capillary zone electrophoresis (CZE) method was developed to separate and analyze eight organic acids (isochlorogenic acid A, 1,3-dicaffeoylquinic acid, 1,5-dicaffeoylquinic acid, chlorogenic acid, isochlorogenic acid B, isochlorogenic acid C, neochlorogenic acid and cryptochlorogenic acid) in honeysuckle and its preparations within 17 minutes, and the linear relationship was good. At the same time, this method applied to the quantitative analysis of eight organic acids in honeysuckle and its preparations. The recovery rate of each organic acid in the sample was 92.6% to 106.8%, and the relative standard deviation was not more than 5.0%. The established method is simple to operate, short in analysis time, and can provide a basis for the quality control of eight organic acids in honeysuckle and its preparations.