Abstract: A highly active Ag-modified La0.6Sr0.4MnO3 catalyst with the perovskite-type structure has been designed and prepared.It is observed experimentally that this catalyst exhibits the activity significantly higher than that of supported precious metal catalysts.O2-TPD shows that modification of Ag+ to the surface of La0.6Sr0.4MnO3 catalyst increases the relative content of the surface O22-/O- species on surface,which are highly reactive toward alcohols.