Abstract:
In this paper, a polycatenar molecular
CTE with coumarin as the central core and triazole PEO dendrons at both sides was synthesized by Click reaction. The structure of
CTE was confirmed by
1H NMR,
13C NMR and elemental analysis. The
CTE micelles loaded with podophyllotoxin were prepared. The critical micelle concentration, drug load and encapsulation efficiency were measured. The results showed that the encapsulation efficiency of the
CTE micelles to podophyllotox in was 56.7%, and the drug load was 34.0%. In addition,
CTE showed excellent selectivity to Fe
3+ among a series of cations, which could be used as chemosensor against Fe
3+.