Abstract:
The chemical constituents of the ethyl acetate fraction of the roots of
Sophora davidii (Franch.) Skeels were isolated and purified by positive phase silica gel column chromatography, Sephadex LH-20 column chromatography, high performance liquid chromatography, and other separation methods. The structures of the compounds were identified by modern spectral techniques. Fifteen compounds were isolated from the ethyl acetate fraction of the roots of
Sophora davidii (Franch.) Skeels and identified as 7-hydroxy-3-(4-hydroxyphenyl)-1-benzopyran-4-one (
1 ), 7,4′-dihydroxy-3′,5′ –dimethoxyisoflavone (
2 ), 7,6′-dihydroxy-3′-methoxy-isoflavone (
3 ), Naringenin (
4 ), 8-demethylfarrerol (
5 ), 5,7,2-trihydroxy-4-methoxyisoflavone (
6 ), Dihydrokaempferol (
7 ), 6-methyl-kaempferol (
8 ), pinostilbene (
7 ), pinosylvine (
10 ), (+)-syringaresinol (
11 ), burselignan (
12 ), 3,3′-bis(3,4-dihydro-6-methoxy-2H- 1-benzopyran) (
13 ), isovanillic acid (
14 ), and medicagol (
15 ). Compounds
1 ,
3~5 ,
7~9 , and
11~14 were isolated from this plant for the first time.