Abstract: This study analyzed the effects of different function bacteria on tobacco continuous cropping obstacle and rhizospheric soil bacteria.Four function bacteria fermented liquid including nitrogen fixing bacteria N251,N839,phosphate solubilizing bacteria P467,P789,metasilicate solubilizing bacteria K175,K391 and cellulolytic bacteria C054,C587 were inoculated in continuous cropping tobacco soil respectively.Four inoculants all promoted the tobacco growth and the cellulolytic bacteria was the best,the mixed bacteria was the second,both significantly higher than the control with plant high 13.4cm,stem diameter 2.73cm and central leaf area 180.77cm2.N251,N839 and C054 could successfully colonize in the tobacco rhizosphere.The number of nitrogen fixing bacteria,phosphate solubilizing bacteria and metasilicate solubilizing bacteria of tobacco rhizosphere inoculating cellulolytic bacteria was more balanced.The effects of inoculants on rhizospheric pseudomonas was different.The inoculants of phosphate solubilizing bacteria and metasilicate solubilizing bacteria could promote other microbial growth.