Abstract:
A new orderly chitosan(CS) membrane was prepared and its biodegradability was studied.Firstly,nonasized chitosan microspheres were prepared from a dilute solution of chitosan in HAc,using sodium tripolyphosphate(TPP) as cross-linking agent.Then,an orderly membrane was cast from a solution of chitosan microspheres and TPP.The result of vitro degradation experiment showed that the orderly cross-linked CS/TPP membrane could be biodegraded by lysozyme,the weight loss of the membrane was about 32% during 16 weeks.The study has indicated that the membranehas order structure and good biodegradability and could be a potential carrier for drug controlled releasing.