三七根茎的化学成分研究(Ⅱ)

Studies on chemical constituents from Rhizomes of Panax Notoginseng(Ⅱ)

摘要: 研究三七Panax notoginseng(Burk.)F.H.Chen根茎的化学成分.利用D101大孔吸附树脂柱、硅胶柱、RP-8和RP-18柱进行化合物的分离纯化,根据其理化性质和光谱数据进行结构鉴定.从三七根茎部分分离鉴定出5个化合物,分别为人参皂苷三七皂苷T5(Notoginsenoside T5,Ⅰ),人参皂苷F1(Gin senoside F1,Ⅱ),人参皂苷F2(Ginsenoside F2,Ⅲ),三七皂苷E(Notoginsenoside E,Ⅳ),人参皂苷Ⅱ(GinsenosideⅡ,Ⅴ).Ⅴ为首次从该植物中分离获得,Ⅰ~Ⅳ为首次从该植物根茎中分离获得.

Abstract: To study the chemical constituents of rhizomes of Panax notoginseng.The compounds were isolated and purified by various chromatogragraphic methods.All compounds were identified on the basis of spectral analysis and physicochemical data.Five compounds were isolated from the rhizomes of Panax notoginseng(Burk.)F.H.Chen and identified as notoginsenoside T5(Ⅰ),ginsenoside F1(Ⅱ),ginsenoside F2(Ⅲ),notoginseno side E(Ⅳ),ginsenoside Ⅱ(Ⅴ).Conclusion Compound Ⅴ was isolated from this plant for the first time and compoundsⅠ—Ⅳ was obtained from the rhizomes of this plant for the first time.